The Madonna Inn is located in San Luis Obispo on the beautiful Central Coast of California, halfway between San Francisco and Los Angeles.

From the north
Take Highway 101 to the Madonna Road exit, approximately 2 miles south of the Highway 1 junction. Use the center lane of the exit ramp and proceed straight after the traffic light.

From the south
Take the Madonna Road exit from Highway 101, approximately 1-1/2 miles north of the Los Osos Valley Road exit. Turn left on Madonna Road, immediately get in the right-hand lane, and turn right at the first traffic light.